Volume 7 ; Issue 2 ; in Month : Jul-Dec (2023) Article No : 174
Archana, Yadav NK, Kumar D.

Abstract
Around the turn of the 20th century, Sir Ronald Fisher popularized the idea of using statistical analysis. Integrating quality into the product is the goal of introducing the design method. The primary means of guaranteeing the quality of the finished product is the application of the Quality by Design (QbD) methodology in the transdermal/topical formulation. The proper application of various design approaches is carried out at the industrial scale because the optimization procedures are necessary for precise research in these disciplines. The fundamentals of QbD design are demonstrated in this review along with how they relate to the various nano-based transdermal and topical formulations.

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