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<title>Journal-of-Pharmaceutical-Research-Science-Technology-ISSUE VOLUME Volume 7 ISSUE Issue 2</title>
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Journal-of-Pharmaceutical-Research-Science-Technology: VOLUME Volume 7 ISSUE Issue 2, Jul-Dec 2023
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<title>Journal-of-Pharmaceutical-Research-Science-Technology-ISSUE VOLUME Volume 7 ISSUE Issue 2</title>
<link>http://ijpp.edwiserinternational.com/rss-feed.php</link>
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		<title>Spectrophotometric-Determination-of-Ampicillin-Using-Chromogenic-Reagents-MBTH-and-PDAC-and-their-Application-in-Pharmaceutical-Formulations</title>
		<pubDate>28-Sep-2023</pubDate>
<link>http://ijpp.edwiserinternational.com/admin/uploads/IsrLQq.pdf</link>
		<author>Siddiqui-MS-Khan-MD-Husain-A-et-al-</author>
		<comments>{http://www.edwiserinternational.com/contact-us.php}</comments>
		<category>Pharmaceutical Science,Medical Science</category>
		<description>{<![CDATA[The present work highlights the spectrophotometric method development and validation for the assay of ampicillin, a broad-spectrum -lactam antibiotic. Two methods have been proposed by employing popular chromogenic reagents viz 3-methyl 2-benzothiazolinone hydrazone (MBTH) and para dimethyl amino cinnamaldehyde (PDAC). Method A involves the coupling of ampicillin with MBTH in the presence of ferric chloride through the oxidative mechanism, resulting in the formation of green coloured solution with a maximum absorption peak at 620 nm. In method B, the condensation reaction of ampicillin with an acidic solution of PDAC gave a coloured reddish-brown complex, showing a maximum absorption peak at 514nm. Linear calibration curve for MBTH and PDAC has been obtained while obeying Beers law in the concentration range of 0.5 -1 and 5-15 g/ml having a good correlation coefficient of 0.9985 and 0.9974 respectively. The sensitivity of the submitted methods was found to be more than the reported methods. Both methods were successfully applied to a pharmaceutical formulation for quantifying the ampicillin effectively. Therefore, the developed spectrophotometric methods can serve as a good analytical assay procedure for ampicillin to undergo quality control in pharmaceutical setups.]]>}</description>
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		<title>Revolutionizing-Imaging-and-Diagnostics-Harnessing-Metallic-Nanoparticles-and-Nanocarriers-for-Cutting-Edge-Theranostics</title>
		<pubDate>15-Nov-2023</pubDate>
<link>http://ijpp.edwiserinternational.com/admin/uploads/hDw61t.pdf</link>
		<author>Priya-SS-Sharma-N-Jahangir-MA</author>
		<comments>{http://www.edwiserinternational.com/contact-us.php}</comments>
		<category>Pharmaceutical Science,Medical Science</category>
		<description>{<![CDATA[The field of medical diagnostics and therapeutics is currently undergoing a transformative revolution, driven by the rapid advancements in nanotechnology. This paper explores the promising potential of metallic nanoparticles and nanocarriers in the realm of theranostics, a fusion of therapy and diagnostics, offering unprecedented opportunities for precision medicine and patient care. The integration of metallic nanoparticles and nanocarriers into medical applications has opened new frontiers for non-invasive imaging and targeted therapy. This review provides an in-depth analysis of metallic nanoparticles, including gold, silver, and magnetic nanoparticles, highlighting their unique physicochemical properties that make them ideal candidates for imaging and therapeutic purposes. Additionally, we discuss the evolution of nanocarriers, such as liposomes, micelles, and dendrimers, and their role in enhancing drug delivery, bioavailability, and treatment specificity. The versatility of metallic nanoparticles and nanocarriers in both imaging and therapeutic applications is showcased through their utilization in areas such as cancer diagnosis, drug delivery, and the management of neurological disorders. Furthermore, their potential to enable real-time monitoring of treatment responses and disease progression is explored, empowering clinicians with essential tools for personalized medicine. Challenges and considerations related to toxicity, biocompatibility, and regulatory hurdles are also discussed, shedding light on the need for further research and collaboration between scientists, clinicians, and regulatory bodies. As metallic nanoparticles and nanocarriers continue to evolve, they promise to revolutionize the landscape of medical diagnostics and therapy, ultimately improving patient outcomes and enhancing the effectiveness of healthcare practices. This paper serves as a comprehensive overview of the current state and future prospects of these groundbreaking technologies, contributing to the advancement of theranostics and its wide-reaching implications for the healthcare industry.]]>}</description>
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		<title>Transdermal-Drug-Delivery-System-An-Insight-into-Recent-Advancements</title>
		<pubDate>14-May-2025</pubDate>
<link>http://ijpp.edwiserinternational.com/admin/uploads/56md43.pdf</link>
		<author>Archana-Yadav-NK-Kumar-D-</author>
		<comments>{http://www.edwiserinternational.com/contact-us.php}</comments>
		<category>Pharmaceutical Science,Medical Science</category>
		<description>{<![CDATA[Around the turn of the 20th century, Sir Ronald Fisher popularized the idea of using statistical analysis. Integrating quality into the product is the goal of introducing the design method. The primary means of guaranteeing the quality of the finished product is the application of the Quality by Design (QbD) methodology in the transdermal/topical formulation. The proper application of various design approaches is carried out at the industrial scale because the optimization procedures are necessary for precise research in these disciplines. The fundamentals of QbD design are demonstrated in this review along with how they relate to the various nano-based transdermal and topical formulations.  ]]>}</description>
		</item><item>
		<title>Monkeypox-History-to-Current-Knowledge</title>
		<pubDate>14-May-2025</pubDate>
<link>http://ijpp.edwiserinternational.com/admin/uploads/8mCqHc.pdf</link>
		<author>Kumar-A-Kumar-A-</author>
		<comments>{http://www.edwiserinternational.com/contact-us.php}</comments>
		<category>Pharmaceutical Science,Medical Science</category>
		<description>{<![CDATA[The monkeypox virus is the source of this zoonotic illness, which has symptoms similar to smallpox. When compared to smallpox, the clinical severity of monkeypox is lower. The term "monkeypox" was created after the disease was found in a location in 1958 where monkeys were housed for scientific purposes. The first human cases of monkeypox were documented in the Congo in 1970. Primarily found in Central and West Africa is the monkeypox virus. The first recorded monkeypox outbreak outside of Africa occurred in the Americas in 2003. Human contact with domestic dogs that were infected with monkeypox was linked to this outbreak.  Monkeypox was not reported as an active case in India until May 31, 2022.  However, India should be prepared as well, just like any other nation, since the number of active cases is rising in non-endemic countries. The virus that causes monkeypox is a double-stranded DNA virus with an envelope. This virus belongs to the genus Orthopoxvirus, which is in the family Poxviridae. The virus that causes monkeypox has been identified in two strains: the West Afican strain and the Congo basin strain. Transmission occurs through very intimate touch that has existed for a long period between humans. Mostly, nasal secretions are the means of transmission for this. Additional means of transmission include direct contact with bodily fluids or fluids released by lesions. Contact with clothing, utensils, and furniture that have fluids released from a monkeypox victim is one of the indirect ways of infection. Human-to-animal transmission of the monkeypox virus occurs when an animal bites or scratches another animal. These creatures include rats, squirrels, apes, monkeys, and their undercooked flesh.   ]]>}</description>
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		<title>An-Epidemiological-Study-of-Typhoid-Patients-from-Rajgir-India</title>
		<pubDate>14-May-2025</pubDate>
<link>http://ijpp.edwiserinternational.com/admin/uploads/p3UfhM.pdf</link>
		<author>Kumar-A-Saurabh-</author>
		<comments>{http://www.edwiserinternational.com/contact-us.php}</comments>
		<category>Pharmaceutical Science,Medical Science</category>
		<description>{<![CDATA[The bacteria Salmonella Typhi is the source of typhoid fever, often known as enteric fever, a potentially fatal illness. It typically spreads by tainted food or drink. After being consumed, Salmonella Typhi bacteria proliferate and enter the bloodstream. The primary signs and symptoms of typhoid fever include: a fever that doesn't go down, headache, aches and pains all over the body, excessive exhaustion, coughing, constipation, poor appetite, lethargy, and diarrhoea. Usually, 1-3 weeks following bacterial exposure, symptoms start to appear. The faecal-oral route, which involves consuming tainted food or drink, is how typhoid disease is spread. The bacterium can be removed from the affected person's stool and contaminate fresh food or water. When treating typhoid fever, cephalosporins are the most often prescribed medications. The most successful cephalosporins nowadays for treating typhoid fever are third generation ones. The Rajgir, a popular tourist destination in the state of Bihar's Nalanda district, served as the study's site. This study comprised forty patients. This report presents the results of many parameters that were studied. There is a great deal of unfinished business in this area, which will allow for the development of a novel treatment plan for the efficient management of this research. It is imperative that chemists at the community level raise public awareness of this issue. The key to preventing this illness is to consume meals and drink only clean, safe water. The most efficient method of preventing the faecal oral route of transmission of this disease is to implement proper sanitation systems, including appropriate drainage systems, in both rural and urban settings.   ]]>}</description>
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